In Impaired Renal and Hepatic Function: Appropriate dosage reductions may be done in patients with impaired renal and hepatic function.
Use in Pregnancy: There is insufficient evidence to recommend the use of trimetazidine in pregnancy. Animal studies do not reveal any teratogenic effect.
Use in Lactation: There is no information on the secretion of trimetazidine into breast milk. However, breastfeeding should be discounted if the use of trimetazidine is considered essential.
Use in Children: There is no experience with trimetazidine in children.